The article Functional Bodybuilding has enlightened me tremendously! But Julian Berriman states that a rapid increase in the volume of a muscle cell, without any increase in the capillary network that supplies the muscle, will lead to an ischaemic enviroment being created. Could you please define iscaemic for me to have a greater understanding of this article?
Ischaemia is a local deficiency of the blood supply to tissues. Consequently, if tissues are not receiving a good blood supply, neither will they be supplied with the many nutrients that our blood brings or be able to flush out any metabolic waste products. One of the main concerns with ishaemia is that it creates a hypoxic environment, that is, a deficiency of oxygen within the tissue. You may have heard the phrase ischaemic heart disease, which refers to the heart becoming diseased through a poor blood supply leading to a relative oxygen deficiency. In this case, the oxygen deficiency causes pain in the tissues (ischaemic pain or chest pains) and may lead to eventual heart attack or failure. Clearly, an ischaemic environment in our muscle cells will also be potentially very hazardous to the health of those cells. At best, such an ischaemic state will limit the growth potential of the cell and at worse will result in breakdown, pain and injury.